产品信息
11837-1-AP targets OLR1/LOX1 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IP, ELISA Application Description
Cited Applications WB, IHC, IF, CoIP
Tested Reactivity Human, Mouse
Cited Reactivity Human, Mouse
Immunogen OLR1/LOX1 fusion protein Ag2437 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name oxidized low density lipoprotein (lectin-like) receptor 1
Synonyms OLR1, Lectin-like oxidized LDL receptor 1, hLOX-1, hLOX1, hLOX 1
Calculated Molecular Weight 273 aa, 31 kDa
Observed Molecular Weight 50-55 kDa
GenBank Accession Number BC022295
Gene Symbol OLR1
Gene ID (NCBI) 4973
RRID AB_2299037
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
UNIPROT ID P78380
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
背景介绍
OLR1/LOX-1 acts as a receptor, in the form of homodimer, that mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein (oxLDL) (PMID: 9052782, 15695803). ORL1 is predominantly expressed in endothelial cells and vascular-rich organs such as the placenta, lung, liver, and brain (PMID: 9828121). OLR1 is a protein containing 273 amino acids with a calculated molecular mass of 31 kDa but an apparent molecular mass of 50 kDa, which may result from the glycosylation of four potential N-linked glycosylation sites located at the C-terminal domain (PMID: 9052782).